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Human MVB12B activation kit by CRISPRa

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SKU
GA113942
MVB12B CRISPRa kit - CRISPR gene activation of human multivesicular body subunit 12B
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA335418 Rabbit Polyclonal Anti-MVB12B Antibody
100 ul
$585.00
RC205093 MVB12B (Myc-DDK-tagged)-Human family with sequence similarity 125, member B (FAM125B), transcript variant 2
10 ug
$300.00

Other products for "MVB12B"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol MVB12B
Locus ID 89853
Components

GA113942G1, MVB12B gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA113942G2, MVB12B gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA113942G3, MVB12B gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001011703, NM_033446
UniProt ID Q9H7P6
Synonyms C9orf28; FAM125B
Summary The protein encoded by this gene is a component of the ESCRT-I complex, a heterotetramer, which mediates the sorting of ubiquitinated cargo protein from the plasma membrane to the endosomal vesicle. ESCRT-I complex plays an essential role in HIV budding and endosomal protein sorting. Depletion and overexpression of this and related protein (MVB12A) inhibit HIV-1 infectivity and induce unusual viral assembly defects, indicating a role for MVB12 subunits in regulating ESCRT-mediated virus budding. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Aug 2011
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Documents
Resources
Other Versions
SKU Description Size Price
KN405093 MVB12B - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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