Human MCM8 activation kit by CRISPRa

SKU
GA113574
MCM8 CRISPRa kit - CRISPR gene activation of human minichromosome maintenance 8 homologous recombination repair factor
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol MCM8
Locus ID 84515
Components

GA113574G1, MCM8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA113574G2, MCM8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA113574G3, MCM8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001281520, NM_001281521, NM_001281522, NM_032485, NM_182802
UniProt ID Q9UJA3
Synonyms C20orf154; dJ967N21.5; POF10
Summary The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the mini-chromosome maintenance proteins is a key component of the pre-replication complex and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein contains the central domain that is conserved among the mini-chromosome maintenance proteins. The encoded protein may interact with other mini-chromosome maintenance proteins and play a role in DNA replication. This gene may be associated with length of reproductive lifespan and menopause. Alternatively spliced transcript variants encoding distinct isoforms have been described. provided by RefSeq, Jul 2013
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Documents
Resources
Other Versions
SKU Description Size Price
KN410269 MCM8 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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