MCM8 Rabbit Polyclonal Antibody
Product Data | |
Application | IHC, WB |
---|---|
Recommended Dilution | WB, IHC |
Reactivity | Human |
Antibody Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | The immunogen for anti-MCM8 antibody: synthetic peptide directed towards the C terminal of human MCM8. Synthetic peptide located within the following region: IRLTEARARLELREEATKEDAEDIVEIMKYSMLGTYSDEFGNLDFERSQH |
Buffer | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Concentration | lot specific |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Shipping | Blue Ice |
Predicted Protein Size | 94 kDa |
Gene Name | minichromosome maintenance 8 homologous recombination repair factor |
Database Link | |
Background | The protein encoded byThis gene is one ofThe highly conserved mini-chromosome maintenance proteins (MCM) that are essential forThe initiation of eukaryotic genome replication.The hexameric protein complex formed byThe mini-chromosome maintenance proteins is a key component ofThe pre-replication complex and may be involved inThe formation of replication forks and inThe recruitment of other DNA replication related proteins.This protein containsThe central domain that is conserved amongThe mini-chromosome maintenance proteins.The encoded protein may interact with other mini-chromosome maintenance proteins and play a role in DNA replication.This gene may be associated with length of reproductive lifespan and menopause. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2013] |
Synonyms | C20orf154; dJ967N21.5; POF10 |
Note | Immunogen Sequence Homology: Pig: 100%; Rat: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Bovine: 100%; Rabbit: 100%; Guinea pig: 100%; Dog: 93%; Zebrafish: 86% |
Reference Data | |
Protein Families | Transcription Factors |
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