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Human ITCH activation kit by CRISPRa

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SKU
GA113254
ITCH CRISPRa kit - CRISPR gene activation of human itchy E3 ubiquitin protein ligase
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA377593 ITCH Rabbit polyclonal Antibody
100 ul
$475.00
RC220408 ITCH (Myc-DDK-tagged)-Human itchy E3 ubiquitin protein ligase homolog (mouse) (ITCH)
10 ug
$789.00

Other products for "ITCH"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol ITCH
Locus ID 83737
Components

GA113254G1, ITCH gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA113254G2, ITCH gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA113254G3, ITCH gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001257137, NM_001257138, NM_031483, NM_001324197, NM_001324198
UniProt ID Q96J02
Synonyms ADMFD; AIF4; AIP4; dJ468O1.1; NAPP1
Summary This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein plays a role in multiple cellular processes including erythroid and lymphoid cell differentiation and the regulation of immune responses. Mutations in this gene are a cause of syndromic multisystem autoimmune disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. provided by RefSeq, Mar 2012
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Other Versions
SKU Description Size Price
KN420408 ITCH - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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