ITCH Rabbit Polyclonal Antibody

SKU
TA377593
ITCH Rabbit polyclonal Antibody
  $475.00
3 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Application ELISA, WB
Recommended Dilution WB,1:500 - 1:1000
ELISA,Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Reactivity Human, Mouse, Rat
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Buffer Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Concentration lot specific
Purification Affinity purification
Conjugation Unconjugated
Storage Store at -20℃. Avoid freeze / thaw cycles.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Predicted Protein Size 103kDa
Gene Name itchy E3 ubiquitin protein ligase
Database Link
Background This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein plays a role in multiple cellular processes including erythroid and lymphoid cell differentiation and the regulation of immune responses. Mutations in this gene are a cause of syndromic multisystem autoimmune disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Synonyms AIF4; AIP4; dJ468O1.1; NAPP1
Reference Data
Protein Categories Allergies and autoimmune diseases, Chemokines, Growth Factors, Intracellular Proteins
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.