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Human SF3B5 activation kit by CRISPRa

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SKU
GA113167
SF3B5 CRISPRa kit - CRISPR gene activation of human splicing factor 3b subunit 5
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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100 ul
$585.00
RC200977 SF3B5 (Myc-DDK-tagged)-Human splicing factor 3b, subunit 5, 10kDa (SF3B5)
10 ug
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Other products for "SF3B5"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol SF3B5
Locus ID 83443
Components

GA113167G1, SF3B5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA113167G2, SF3B5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA113167G3, SF3B5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_031287
UniProt ID Q9BWJ5
Synonyms SF3b10; Ysf3
Summary Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex, a constituent of the spliceosome (PubMed:27720643, PubMed:28781166). SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA (PubMed:12234937).UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN400977 SF3B5 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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