Human RAB1B activation kit by CRISPRa

SKU GA113146

RAB1B CRISPRa kit - CRISPR gene activation of human RAB1B, member RAS oncogene family

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: RAB1B
• Locus ID: 81876
• Components:

  GA113146G1, RAB1B gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA113146G2, RAB1B gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA113146G3, RAB1B gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_030981
• UniProt ID: Q9H0U4
• Synonyms: RAB1B, member RAS oncogene family; small GTP-binding protein
• Summary: Members of the RAB protein family, such as RAB1B, are low molecular mass monomeric GTPases localized on the cytoplasmic surfaces of distinct membrane-bound organelles. RAB1B functions in the early secretory pathway and is essential for vesicle transport between the endoplasmic reticulum (ER) and Golgi (Chen et al., 1997 [PubMed 9030196]; Alvarez et al., 2003 [PubMed 12802079]).[supplied by OMIM, Jan 2009]