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Human CLPB activation kit by CRISPRa

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SKU
GA113073
CLPB CRISPRa kit - CRISPR gene activation of human ClpB homolog, mitochondrial AAA ATPase chaperonin
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA335442 Rabbit Polyclonal Anti-CLPB Antibody
100 ul
$585.00
RC203013 CLPB (Myc-DDK-tagged)-Human ClpB caseinolytic peptidase B homolog (E. coli) (CLPB)
10 ug
$647.00

Other products for "CLPB"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol CLPB
Locus ID 81570
Components

GA113073G1, CLPB gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA113073G2, CLPB gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA113073G3, CLPB gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001258392, NM_001258393, NM_001258394, NM_030813
UniProt ID Q9H078
Synonyms ANKCLB; HSP78; MEGCANN; MGCA7; SKD3
Summary This gene belongs to the ATP-ases associated with diverse cellular activities (AAA+) superfamily. Members of this superfamily form ring-shaped homo-hexamers and have highly conserved ATPase domains that are involved in various processes including DNA replication, protein degradation and reactivation of misfolded proteins. All members of this family hydrolyze ATP through their AAA+ domains and use the energy generated through ATP hydrolysis to exert mechanical force on their substrates. In addition to an AAA+ domain, the protein encoded by this gene contains a C-terminal D2 domain, which is characteristic of the AAA+ subfamily of Caseinolytic peptidases to which this protein belongs. It cooperates with Hsp70 in the disaggregation of protein aggregates. Allelic variants of this gene are associated with 3-methylglutaconic aciduria, which causes cataracts and neutropenia. Alternative splicing results in multiple transcript variants. provided by RefSeq, Apr 2015
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Documents
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Other Versions
SKU Description Size Price
KN403013 CLPB - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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