Human RNF34 activation kit by CRISPRa

SKU
GA112860
RNF34 CRISPRa kit - CRISPR gene activation of human ring finger protein 34
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol RNF34
Locus ID 80196
Components

GA112860G1, RNF34 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA112860G2, RNF34 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA112860G3, RNF34 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001256858, NM_025126, NM_194271
UniProt ID Q969K3
Synonyms CARP-1; CARP1; hRFI; RFI; RIF; RIFF
Summary The protein encoded by this gene contains a RINF finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein interacts with DNAJA3/hTid-1, which is a DnaJ protein reported to function as a modulator of apoptosis. Overexpression of this gene in Hela cells was shown to confer the resistance to TNF-alpha induced apoptosis, suggesting an anti-apoptotic function of this protein. This protein can be cleaved by caspase-3 during the induction of apoptosis. This protein also targets p53 and phospho-p53 for degradation. Alternatively splicing results in multiple transcript variants encoding distinct isoforms. provided by RefSeq, Feb 2012
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Documents
Resources
Other Versions
SKU Description Size Price
KN403191 RNF34 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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