Human NANOG activation kit by CRISPRa

SKU GA112732

NANOG CRISPRa kit - CRISPR gene activation of human Nanog homeobox

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: NANOG
• Locus ID: 79923
• Components:

  GA112732G1, NANOG gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA112732G2, NANOG gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA112732G3, NANOG gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001297698, NM_024865
• UniProt ID: Q9H9S0
• Summary: The protein encoded by this gene is a DNA binding homeobox transcription factor involved in embryonic stem (ES) cell proliferation, renewal, and pluripotency. The encoded protein can block ES cell differentiation and can also autorepress its own expression in differentiating cells. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015]