Human CCDC134 activation kit by CRISPRa

SKU
GA112700
CCDC134 CRISPRa kit - CRISPR gene activation of human coiled-coil domain containing 134
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol CCDC134
Locus ID 79879
Components

GA112700G1, CCDC134 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA112700G2, CCDC134 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA112700G3, CCDC134 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001304797, NM_024821
UniProt ID Q9H6E4
Summary In extracellular secreted form, promotes proliferation and activation of CD8(+) T cells, suggesting a cytokine-like function (PubMed:25125657). Enhances cytotoxic anti-tumor activity of CD8(+) T cells (PubMed:25125657). May inhibit ERK and JNK signaling activity (PubMed:18087676, PubMed:23070808). May suppress cell migration and invasion activity, via its effects on ERK and JNK signaling (PubMed:23070808).UniProtKB/Swiss-Prot Function
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Documents
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Other Versions
SKU Description Size Price
KN404377 CCDC134 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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