Human MMEL1 activation kit by CRISPRa

SKU GA112418

MMEL1 CRISPRa kit - CRISPR gene activation of human membrane metalloendopeptidase like 1

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: MMEL1
• Locus ID: 79258
• Components:

  GA112418G1, MMEL1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA112418G2, MMEL1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA112418G3, MMEL1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_033467
• UniProt ID: Q495T6
• Synonyms: MMEL2; NEP2; NEPII; NL1; NL2; SEP
• Summary: The protein encoded by this gene is a member of the neutral endopeptidase (NEP) or membrane metallo-endopeptidase (MME) family. Family members play important roles in pain perception, arterial pressure regulation, phosphate metabolism and homeostasis. This protein is a type II transmembrane protein and is thought to be expressed as a secreted protein. This gene is expressed mainly in testis with weak expression in the brain, kidney, and heart. [provided by RefSeq, Jul 2008]