Human FBXL15 activation kit by CRISPRa

SKU
GA112405
FBXL15 CRISPRa kit - CRISPR gene activation of human F-box and leucine rich repeat protein 15
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol FBXL15
Locus ID 79176
Components

GA112405G1, FBXL15 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA112405G2, FBXL15 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA112405G3, FBXL15 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_024326
UniProt ID Q9H469
Synonyms Fbl15; FBXO37; JET; PSD
Summary Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of SMURF1, thereby acting as a positive regulator of the BMP signaling pathway. Required for dorsal/ventral pattern formation and bone mass maintenance. Also mediates ubiquitination of SMURF2 and WWP2.UniProtKB/Swiss-Prot Function
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Documents
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Other Versions
SKU Description Size Price
KN406363 FBXL15 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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