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Human DERL1 activation kit by CRISPRa

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SKU
GA112378
DERL1 CRISPRa kit - CRISPR gene activation of human derlin 1
  $1,657.00
4 Weeks*

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Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol DERL1
Locus ID 79139
Components

GA112378G1, DERL1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA112378G2, DERL1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA112378G3, DERL1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001134671, NM_001330601, NM_024295, NM_001363963
UniProt ID Q9BUN8
Synonyms DER-1; DER1; derlin-1
Summary The protein encoded by this gene is a member of the derlin family. Members of this family participate in the ER-associated degradation response and retrotranslocate misfolded or unfolded proteins from the ER lumen to the cytosol for proteasomal degradation. This protein recognizes substrate in the ER and works in a complex to retrotranslocate it across the ER membrane into the cytosol. This protein may select cystic fibrosis transmembrane conductance regulator protein (CFTR) for degradation as well as unfolded proteins in Alzheimer's disease. Alternative splicing results in multiple transcript variants that encode different protein isoforms. provided by RefSeq, Aug 2012
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Documents
Resources
Other Versions
SKU Description Size Price
KN400959 DERL1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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