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DERL1 Rabbit Polyclonal Antibody

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SKU
TA301554
Rabbit Polyclonal Antibody against Derlin-1
Size:
100 ul
Conjugation:
Unconjugated
  $610.00
2 Weeks*
Bulk/Customize

Frequently Bought Together (2)

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View other "DERL1 or NM_024295" antibodies

Specifications
Specifications
Product Data
Application ICC/IF, IHC, WB
Recommended Dilution Immunohistochemistry: 5-10 ug/ml, Immunocytochemistry/ Immunofluorescence: 1:2000, Western Blot: 1:1000-1:5000, Immunohistochemistry-Paraffin: 5-10 ug/ml
Reactivity Dog, Human
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen A synthetic peptide made to the C-terminal region of the human Derlin-1 protein sequence (between residues 200-251).
Buffer Tris-citrate/phosphate, pH 7-8, 0.1% sodium Azide
Purification Immunogen affinity purified
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Gene Name derlin 1
Database Link
Background Derlin-1 is a channel-like protein, found in the ER membrane, responsible for degrading and funneling misfolded proteins and other cellular debris into the appropriate degradative pathways within the cell.
Synonyms DER-1; DER1; derlin-1
Reference Data
Protein Categories Membrane Proteins
Protein Families Druggable Genome, Transmembrane
Protein Pathways Amyotrophic lateral sclerosis (ALS)
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Documents
Resources

file-alt Citations

BRCA1 mediates protein homeostasis through the ubiquitination of PERK and IRE1
Hromas, Srinivasan, Yang et al
iScience (2022) 25 (12), 105626 DOI: 10.1016/j.isci.2022.105626
Cited by 19
AI Summary: In this study, the OriGene Technologies Anti-DERLIN 1 antibody (Cat# TA301554) was used to detect DERLIN 1 protein levels, contributing to the analysis of protein homeostasis mechanisms regulated by BRCA1.
Snippet: AB_626761 Anti-Cyclophilin B Abcam Cat# ab 178397 Anti-Cyclophilin B ThermoFisher Cat# MA5-31392;RRID: AB_2787028 Anti-DERLIN 1 Santa Cruz Biotech Cat# sc-293385 Anti-DERLIN 1 Origene Technologies Cat# TA301554 Anti-GAPDH Cell Signaling Cat# 2118;RRID: AB_561053 Anti-IRE1 Cell Signaling Cat# 3294;RRID: AB_823545 Anti-IRE1 (phospho) Abcam Cat# ab124945
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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