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Human ZP4 activation kit by CRISPRa

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SKU
GA111745
ZP4 CRISPRa kit - CRISPR gene activation of human zona pellucida glycoprotein 4
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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100 ul
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RC210177 ZP4 (Myc-DDK-tagged)-Human zona pellucida glycoprotein 4 (ZP4)
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Other products for "ZP4"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol ZP4
Locus ID 57829
Components

GA111745G1, ZP4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA111745G2, ZP4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA111745G3, ZP4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_021186
UniProt ID Q12836
Synonyms ZBP; Zp-4; ZP1; ZPB
Summary The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. The nascent protein contains a N-terminal signal peptide sequence, a conserved ZP domain, a consensus furin cleavage site, and a C-terminal transmembrane domain. It is hypothesized that furin cleavage results in release of the mature protein from the plasma membrane for subsequent incorporation into the zona pellucida matrix. However, the requirement for furin cleavage in this process remains controversial based on mouse studies. Previously, this gene has been referred to as ZP1 or ZPB and thought to have similar functions as mouse Zp1. However, a human gene with higher similarity and chromosomal synteny to mouse Zp1 has been assigned the symbol ZP1 and this gene has been assigned the symbol ZP4. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN410177 ZP4 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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