Human ARID1B activation kit by CRISPRa

SKU GA111533

ARID1B CRISPRa kit - CRISPR gene activation of human AT-rich interaction domain 1B

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: ARID1B
• Locus ID: 57492
• Components:

  GA111533G1, ARID1B gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA111533G2, ARID1B gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA111533G3, ARID1B gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_017519, NM_020732, NM_175863, NM_001346813, NM_001363725
• UniProt ID: Q8NFD5
• Synonyms: 6A3-5; BAF250B; BRIGHT; DAN15; ELD/OSA1; MRD12; OSA2; P250R
• Summary: This locus encodes an AT-rich DNA interacting domain-containing protein. The encoded protein is a component of the SWI/SNF chromatin remodeling complex and may play a role in cell-cycle activation. The protein encoded by this locus is similar to AT-rich interactive domain-containing protein 1A. These two proteins function as alternative, mutually exclusive ARID-subunits of the SWI/SNF complex. The associated complexes play opposing roles. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2016]