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Human BTNL2 activation kit by CRISPRa

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SKU
GA111160
BTNL2 CRISPRa kit - CRISPR gene activation of human butyrophilin like 2
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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RC214359 BTNL2 (Myc-DDK-tagged)-Human butyrophilin-like 2 (MHC class II associated) (BTNL2)
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Other products for "BTNL2"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol BTNL2
Locus ID 56244
Components

GA111160G1, BTNL2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA111160G2, BTNL2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA111160G3, BTNL2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001304561, NM_019602
Synonyms BTL-II; BTN7; HSBLMHC1; SS2
Summary This gene encodes a major histocompatibility complex, class II associated, type I transmembrane protein which belongs to the butyrophilin-like B7 family of immunoregulators. It is thought to be involved in immune surveillance, serving as a negative T-cell regulator by decreasing T-cell proliferation and cytokine release. The encoded protein contains an N-terminal signal peptide, two pairs of immunoglobulin-like domains, separated by a heptad peptide sequence, and a C-terminal transmembrane domain. Naturally occurring mutations in this gene are associated with sarcoidosis, rheumatoid arthritis, ulcerative colitis, inflammatory bowel disease, myositis, type 1 diabetes, systemic lupus erythematosus, acute coronary syndrome, and prostate cancer. provided by RefSeq, May 2017
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Documents
Resources
Other Versions
SKU Description Size Price
KN414359 BTNL2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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