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Human WDR41 activation kit by CRISPRa

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SKU
GA110648
WDR41 CRISPRa kit - CRISPR gene activation of human WD repeat domain 41
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA365146 WDR41 rabbit polyclonal antibody
100 ul
$310.00
RC201693 WDR41 (Myc-DDK-tagged)-Human WD repeat domain 41 (WDR41)
10 ug
$289.00 $686.00

Other products for "WDR41"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol WDR41
Locus ID 55255
Components

GA110648G1, WDR41 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA110648G2, WDR41 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA110648G3, WDR41 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_018268
UniProt ID Q9HAD4
Synonyms MSTP048
Summary Non-catalytic component of the C9orf72-SMCR8 complex, a complex that has guanine nucleotide exchange factor (GEF) activity and regulates autophagy (PubMed:27193190, PubMed:27103069, PubMed:27617292, PubMed:28195531). The C9orf72-SMCR8 complex promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB8A and RAB39B into their active GTP-bound form, thereby promoting autophagosome maturation (PubMed:27103069). The C9orf72-SMCR8 complex also acts as a negative regulator of autophagy initiation by interacting with the ATG1/ULK1 kinase complex and inhibiting its protein kinase activity (PubMed:27103069, PubMed:27617292).UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN401693 WDR41 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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