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Human ERCC6L activation kit by CRISPRa

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SKU
GA110286
ERCC6L CRISPRa kit - CRISPR gene activation of human ERCC excision repair 6 like, spindle assembly checkpoint helicase
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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100 ul
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RC223966 ERCC6L (Myc-DDK-tagged)-Human excision repair cross-complementing rodent repair deficiency, complementation group 6-like (ERCC6L)
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Other products for "ERCC6L"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol ERCC6L
Locus ID 54821
Components

GA110286G1, ERCC6L gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA110286G2, ERCC6L gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA110286G3, ERCC6L gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001009954, NM_017669
UniProt ID Q2NKX8
Summary This gene encodes a member of the SWItch/Sucrose Non-Fermentable (SWI/SNF2) family of proteins, and contains a SNF2-like ATPase domain and a PICH family domain. One distinguishing feature of this SWI/SNF protein family member is that during interphase, the protein is excluded from the nucleus, and only associates with chromatin after the nuclear envelope has broken down. This protein is a DNA translocase that is thought to bind double-stranded DNA that is exposed to stretching forces, such as those exerted by the mitotic spindle. This protein associates with ribosomal DNA and ultra-fine DNA bridges (UFBs), fine structures that connect sister chromatids during anaphase at some sites such as fragile sites, telomeres and centromeres. This gene is required for the faithful segregation of sister chromatids during mitosis, and the ATPase activity of this protein required for the resolution of UFBs before cytokinesis. provided by RefSeq, May 2017
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Documents
Resources
Other Versions
SKU Description Size Price
KN423966 ERCC6L - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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