Human CDC40 activation kit by CRISPRa

SKU GA109763

CDC40 CRISPRa kit - CRISPR gene activation of human cell division cycle 40

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: CDC40
• Locus ID: 51362
• Components:

  GA109763G1, CDC40 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA109763G2, CDC40 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA109763G3, CDC40 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_015891
• UniProt ID: O60508
• Synonyms: EHB3; PRP17; PRPF17
• Summary: Pre-mRNA splicing occurs in two sequential transesterification steps. The protein encoded by this gene is found to be essential for the catalytic step II in pre-mRNA splicing process. It is found in the spliceosome, and contains seven WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp17 protein, which functions in two different cellular processes: pre-mRNA splicing and cell cycle progression. It suggests that this protein may play a role in cell cycle progression. [provided by RefSeq, Jul 2008]