Human S2P (MBTPS2) activation kit by CRISPRa

SKU
GA109761
MBTPS2 CRISPRa kit - CRISPR gene activation of human membrane bound transcription factor peptidase, site 2
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol MBTPS2
Locus ID 51360
Components

GA109761G1, S2P gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA109761G2, S2P gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA109761G3, S2P gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_015884
UniProt ID O43462
Synonyms BRESEK; IFAP; KFSD; KFSDX; OLMSX; S2P
Summary This gene encodes a intramembrane zinc metalloprotease, which is essential in development. This protease functions in the signal protein activation involved in sterol control of transcription and the ER stress response. Mutations in this gene have been associated with ichthyosis follicularis with atrichia and photophobia (IFAP syndrome); IFAP syndrome has been quantitatively linked to a reduction in cholesterol homeostasis and ER stress response.provided by RefSeq, Aug 2009
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Other Versions
SKU Description Size Price
KN418791 MBTPS2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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