Human ABCA12 activation kit by CRISPRa

SKU GA108779

ABCA12 CRISPRa kit - CRISPR gene activation of human ATP binding cassette subfamily A member 12

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: ABCA12
• Locus ID: 26154
• Components:

  GA108779G1, ABCA12 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA108779G2, ABCA12 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA108779G3, ABCA12 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_015657, NM_173076, NR_103740
• UniProt ID: Q86UK0
• Synonyms: ARCI4A; ARCI4B; ICR2B; LI2
• Summary: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This encoded protein is a member of the ABC1 subfamily, which is the only major ABC subfamily found exclusively in multicellular eukaryotes. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]