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Human ZNF451 activation kit by CRISPRa

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SKU
GA108711
ZNF451 CRISPRa kit - CRISPR gene activation of human zinc finger protein 451
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA383566 ZNF451 Rabbit polyclonal Antibody
100 ul
$410.00
RC215720 ZNF451 (Myc-DDK-tagged)-Human zinc finger protein 451 (ZNF451), transcript variant 1
10 ug
$924.00

Other products for "ZNF451"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol ZNF451
Locus ID 26036
Components

GA108711G1, ZNF451 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA108711G2, ZNF451 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA108711G3, ZNF451 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001031623, NM_001257273, NM_015555
UniProt ID Q9Y4E5
Synonyms COASTER; dJ417I1.1
Summary E3 SUMO-protein ligase; has a preference for SUMO2 and SUMO3 and facilitates UBE2I/UBC9-mediated sumoylation of target proteins (PubMed:26524493, PubMed:26524494). Plays a role in protein SUMO2 modification in response to stress caused by DNA damage and by proteasome inhibitors (in vitro). Required for MCM4 sumoylation (By similarity). Has no activity with SUMO1 (PubMed:26524493). Preferentially transfers an additional SUMO2 chain onto the SUMO2 consensus site 'Lys-11' (PubMed:26524493). Negatively regulates transcriptional activation mediated by the SMAD4 complex in response to TGF-beta signaling. Inhibits EP300-mediated acetylation of histone H3 at 'Lys-9' (PubMed:24324267). Plays a role in regulating the transcription of AR targets (PubMed:18656483).UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN215720 ZNF451 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN215720BN ZNF451 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN215720LP ZNF451 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN215720RB ZNF451 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN415720 ZNF451 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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