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Human PHLDA3 activation kit by CRISPRa

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SKU
GA108434
PHLDA3 CRISPRa kit - CRISPR gene activation of human pleckstrin homology like domain family A member 3
  $1,657.00
4 Weeks*

Frequently Bought Together (1)

RC206751 PHLDA3 (Myc-DDK-tagged)-Human pleckstrin homology-like domain, family A, member 3 (PHLDA3)
10 ug
$150.00

Other products for "PHLDA3"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PHLDA3
Locus ID 23612
Components

GA108434G1, PHLDA3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA108434G2, PHLDA3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA108434G3, PHLDA3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_012396, NR_073080, N94465
UniProt ID Q9Y5J5
Synonyms TIH1
Summary p53/TP53-regulated repressor of Akt/AKT1 signaling. Represses AKT1 by preventing AKT1-binding to membrane lipids, thereby inhibiting AKT1 translocation to the cellular membrane and activation. Contributes to p53/TP53-dependent apoptosis by repressing AKT1 activity. Its direct transcription regulation by p53/TP53 may explain how p53/TP53 can negatively regulate AKT1. May act as a tumor suppressor.UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN406751 PHLDA3 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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