Human ADAT1 activation kit by CRISPRa

SKU GA108378

ADAT1 CRISPRa kit - CRISPR gene activation of human adenosine deaminase tRNA specific 1

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: ADAT1
• Locus ID: 23536
• Components:

  GA108378G1, ADAT1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA108378G2, ADAT1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA108378G3, ADAT1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001324444, NM_001324445, NM_001324446, NM_001324448, NM_001324449, NM_001324450, NM_001324451, NM_001324452, NM_001324453, NM_012091, NR_036460
• UniProt ID: Q9BUB4
• Synonyms: HADAT1
• Summary: This gene is a member of the ADAR (adenosine deaminase acting on RNA) family. Using site-specific adenosine modification, proteins encoded by these genes participate in the pre-mRNA editing of nuclear transcripts. The protein encoded by this gene, tRNA-specific adenosine deaminase 1, is responsible for the deamination of adenosine 37 to inosine in eukaryotic tRNA. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2010]