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Human PACS2 activation kit by CRISPRa

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SKU
GA108154
PACS2 CRISPRa kit - CRISPR gene activation of human phosphofurin acidic cluster sorting protein 2
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA339235 Rabbit Polyclonal Anti-PACS2
100 ul
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RC218762 PACS2 (Myc-DDK-tagged)-Human phosphofurin acidic cluster sorting protein 2 (PACS2), transcript variant 1
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Other products for "PACS2"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PACS2
Locus ID 23241
Components

GA108154G1, PACS2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA108154G2, PACS2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA108154G3, PACS2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001100913, NM_001243127, NM_015197
UniProt ID Q86VP3
Synonyms PACS-2; PACS1L
Summary Multifunctional sorting protein that controls the endoplasmic reticulum (ER)-mitochondria communication, including the apposition of mitochondria with the ER and ER homeostasis. In addition, in response to apoptotic inducer, translocates BIB to mitochondria, which initiates a sequence of events including the formation of mitochondrial truncated BID, the release of cytochrome c, the activation of caspase-3 thereby causing cell death. May also be involved in ion channel trafficking, directing acidic cluster-containing ion channels to distinct subcellular compartments.UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
KN409593 PACS2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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