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Human PHLPP (PHLPP1) activation kit by CRISPRa

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SKU
GA108152
PHLPP1 CRISPRa kit - CRISPR gene activation of human PH domain and leucine rich repeat protein phosphatase 1
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA319850 Rabbit Polyclonal PHLPP1 Antibody
100 ug
$640.00
RC203930 PHLPP1 (Myc-DDK-tagged)-Human PH domain and leucine rich repeat protein phosphatase 1 (PHLPP1)
10 ug
$1,049.00

Other products for "PHLPP1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PHLPP1
Locus ID 23239
Components

GA108152G1, PHLPP gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA108152G2, PHLPP gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA108152G3, PHLPP gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_194449
UniProt ID O60346
Synonyms PHLPP; PLEKHE1; PPM3A; SCOP
Summary This gene encodes a member of the serine/threonine phosphatase family. The encoded protein promotes apoptosis by dephosphorylating and inactivating the serine/threonine kinase Akt, and functions as a tumor suppressor in multiple types of cancer. Increased expression of this gene may also play a role in obesity and type 2 diabetes by interfering with Akt-mediated insulin signaling. provided by RefSeq, Dec 2011
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Documents
Resources
Other Versions
SKU Description Size Price
KN403930 PHLPP1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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