Human MLC1 activation kit by CRISPRa

SKU GA108126

MLC1 CRISPRa kit - CRISPR gene activation of human modulator of VRAC current 1

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: MLC1
• Locus ID: 23209
• Components:

  GA108126G1, MLC1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA108126G2, MLC1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA108126G3, MLC1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_015166, NM_139202
• UniProt ID: Q15049
• Synonyms: LVM; MLC; VL
• Summary: The function of this gene product is unknown; however, homology to other proteins suggests that it may be an integral membrane transporter. Mutations in this gene have been associated with megalencephalic leukoencephalopathy with subcortical cysts, an autosomal recessive neurological disorder. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]