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Human KDM6B activation kit by CRISPRa

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SKU
GA108063
KDM6B CRISPRa kit - CRISPR gene activation of human lysine demethylase 6B
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA319844 Rabbit Polyclonal JMJD3 Antibody
100 ug
$640.00
RC219461 KDM6B (Myc-DDK-tagged)-Human lysine (K)-specific demethylase 6B (KDM6B)
10 ug
$2,120.00

Other products for "KDM6B"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol KDM6B
Locus ID 23135
Components

GA108063G1, KDM6B gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA108063G2, KDM6B gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA108063G3, KDM6B gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001080424, NM_001348716
UniProt ID O15054
Synonyms JMJD3
Summary The protein encoded by this gene is a lysine-specific demethylase that specifically demethylates di- or tri-methylated lysine 27 of histone H3 (H3K27me2 or H3K27me3). H3K27 trimethylation is a repressive epigenetic mark controlling chromatin organization and gene silencing. This protein can also demethylate non-histone proteins such as retinoblastoma protein. Through its demethylation actvity this gene influences cellular differentiation and development, tumorigenesis, inflammatory diseases, and neurodegenerative diseases. This protein has two classical nuclear localization signals at its N-terminus. Alternative splicing results in multiple transcript variants encoding distinct isoforms. provided by RefSeq, Feb 2017
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Documents
Resources
Other Versions
SKU Description Size Price
KN419461 KDM6B - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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