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Human RRP1B activation kit by CRISPRa

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SKU
GA108019
RRP1B CRISPRa kit - CRISPR gene activation of human ribosomal RNA processing 1B
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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100 ul
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RC206073 RRP1B (Myc-DDK-tagged)-Human ribosomal RNA processing 1 homolog B (S. cerevisiae) (RRP1B)
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Other products for "RRP1B"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol RRP1B
Locus ID 23076
Components

GA108019G1, RRP1B gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA108019G2, RRP1B gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA108019G3, RRP1B gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_015056
UniProt ID Q14684
Synonyms KIAA0179; Nnp1; NNP1L; PPP1R136; RRP1
Summary Positively regulates DNA damage-induced apoptosis by acting as a transcriptional coactivator of proapoptotic target genes of the transcriptional activator E2F1 (PubMed:20040599). Likely to play a role in ribosome biogenesis by targeting serine/threonine protein phosphatase PP1 to the nucleolus (PubMed:20926688). Involved in regulation of mRNA splicing (By similarity). Inhibits SIPA1 GTPase activity (By similarity). Involved in regulating expression of extracellular matrix genes (By similarity). Associates with chromatin and may play a role in modulating chromatin structure (PubMed:19710015).UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN406073 RRP1B - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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