Human TMCC1 activation kit by CRISPRa
Specifications
| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
|---|---|
| Target Symbol | TMCC1 |
| Locus ID | 23023 |
| Components |
GA107976G1, TMCC1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107976G2, TMCC1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107976G3, TMCC1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| OTI Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_001017395, NM_001128224, NM_015008, NR_033361, NM_001349263, NM_001349264, NM_001349265, NM_001349266, NM_001349268, NM_001349269, NM_001349270, NM_001349271, NM_001349272, NM_001349273, NM_001349274, NM_001349275, NM_001349276 |
| UniProt ID | O94876 |
| Synonyms | DKFZp686M0169; FLJ42680 |
| Summary | Endoplasmic reticulum membrane protein that promotes endoplasmic reticulum-associated endosome fission (PubMed:30220460). Localizes to contact sites between the endoplasmic reticulum and endosomes and acts by promoting recruitment of the endoplasmic reticulum to endosome tubules for fission (PubMed:30220460). Endosome membrane fission of early and late endosomes is essential to separate regions destined for lysosomal degradation from carriers to be recycled to the plasma membrane (PubMed:30220460).UniProtKB/Swiss-Prot Function |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| KN408078 | TMCC1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 kit |
$1,657.00
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Citations
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