Human TMCC1 activation kit by CRISPRa

SKU
GA107976
TMCC1 CRISPRa kit - CRISPR gene activation of human transmembrane and coiled-coil domain family 1
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol TMCC1
Locus ID 23023
Components

GA107976G1, TMCC1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA107976G2, TMCC1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA107976G3, TMCC1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001017395, NM_001128224, NM_015008, NR_033361, NM_001349263, NM_001349264, NM_001349265, NM_001349266, NM_001349268, NM_001349269, NM_001349270, NM_001349271, NM_001349272, NM_001349273, NM_001349274, NM_001349275, NM_001349276
UniProt ID O94876
Synonyms DKFZp686M0169; FLJ42680
Summary Endoplasmic reticulum membrane protein that promotes endoplasmic reticulum-associated endosome fission (PubMed:30220460). Localizes to contact sites between the endoplasmic reticulum and endosomes and acts by promoting recruitment of the endoplasmic reticulum to endosome tubules for fission (PubMed:30220460). Endosome membrane fission of early and late endosomes is essential to separate regions destined for lysosomal degradation from carriers to be recycled to the plasma membrane (PubMed:30220460).UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN408078 TMCC1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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