OriGene Logo

Customer Login

Checkout as a new customer

Creating an account has many benefits:

  • See order and shipping status
  • Track order history
  • Check out faster
Create an Account

Human CNOT1 activation kit by CRISPRa

Be the first to review this product
SKU
GA107973
CNOT1 CRISPRa kit - CRISPR gene activation of human CCR4-NOT transcription complex subunit 1
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA374925 CNOT1 Rabbit polyclonal Antibody
100 ul
$410.00
RC206903 CNOT1 (Myc-DDK-tagged)-Human CCR4-NOT transcription complex, subunit 1 (CNOT1), transcript variant 2
10 ug
$2,122.00

Other products for "CNOT1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol CNOT1
Locus ID 23019
Components

GA107973G1, CNOT1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA107973G2, CNOT1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA107973G3, CNOT1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001265612, NM_016284, NM_206999, NR_049763
UniProt ID A5YKK6
Synonyms AD-005; CDC39; NOT1; NOT1H
Summary Scaffolding component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Its scaffolding function implies its interaction with the catalytic complex module and diverse RNA-binding proteins mediating the complex recruitment to selected mRNA 3' UTRs. Involved in degradation of AU-rich element (ARE)-containing mRNAs probably via association with ZFP36. Mediates the recruitment of the CCR4-NOT complex to miRNA targets and to the RISC complex via association with TNRC6A, TNRC6B or TNRC6C. Acts as a transcriptional repressor. Represses the ligand-dependent transcriptional activation by nuclear receptors. Involved in the maintenance of embryonic stem (ES) cell identity.UniProtKB/Swiss-Prot Function
Reviews
Write Review
 
 
 
 
 

Be the first to review this product

Please note:
Only reviews with images are eligible for a $20/20€ Amazon gift card.
Reviews without images are eligible for a $10/10€ Amazon gift card.
For more details about the terms and conditions, please visit the promotion page.

Review image
Documents
Resources
Other Versions
SKU Description Size Price
KN206903 CNOT1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN206903BN CNOT1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN206903LP CNOT1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN206903RB CNOT1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN406903 CNOT1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Related Products