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Human MAPKBP1 activation kit by CRISPRa

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SKU
GA107963
MAPKBP1 CRISPRa kit - CRISPR gene activation of human mitogen-activated protein kinase binding protein 1
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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100 ul
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RC221849 MAPKBP1 (Myc-DDK-tagged)-Human mitogen-activated protein kinase binding protein 1 (MAPKBP1), transcript variant 1
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Other products for "MAPKBP1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol MAPKBP1
Locus ID 23005
Components

GA107963G1, MAPKBP1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA107963G2, MAPKBP1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA107963G3, MAPKBP1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001128608, NM_001265611, NM_014994, NR_049761, NR_049762
UniProt ID O60336
Synonyms JNKBP-1
Summary This gene encodes a scaffold protein that regulates the JNK (c-Jun N-terminal kinase) and NOD2 (nucleotide-binding oligomerization domain-containing protein 2) signaling pathways. The encoded protein interacts with another related JNK pathway scaffold protein, WDR62, via a conserved dimerization domain, and enhances JNK signaling. This protein may play a role in bacterial immunity by binding to the NOD2 receptor and negatively regulating downstream antibacterial and pro-inflammatory signaling. Mutations in this gene that impair cellular localization of the encoded protein cause a form of nephronophthisis, an autosomal-recessive kidney disorder, in human patients. provided by RefSeq, May 2017
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Documents
Resources
Other Versions
SKU Description Size Price
KN421849 MAPKBP1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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