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Human DKK1 activation kit by CRISPRa

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SKU
GA107930
DKK1 CRISPRa kit - CRISPR gene activation of human dickkopf WNT signaling pathway inhibitor 1
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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100 ug
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RC200094 DKK1 (Myc-DDK-tagged)-Human dickkopf homolog 1 (Xenopus laevis) (DKK1)
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Other products for "DKK1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol DKK1
Locus ID 22943
Components

GA107930G1, DKK1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA107930G2, DKK1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA107930G3, DKK1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_012242
UniProt ID O94907
Synonyms DKK-1; SK
Summary This gene encodes a member of the dickkopf family of proteins. Members of this family are secreted proteins characterized by two cysteine-rich domains that mediate protein-protein interactions. The encoded protein binds to the LRP6 co-receptor and inhibits beta-catenin-dependent Wnt signaling. This gene plays a role in embryonic development and may be important in bone formation in adults. Elevated expression of this gene has been observed in numerous human cancers and this protein may promote proliferation, invasion and growth in cancer cell lines. provided by RefSeq, Sep 2017
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Documents
Resources
Other Versions
SKU Description Size Price
KN400094 DKK1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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