Human DDX42 activation kit by CRISPRa

SKU GA107793

DDX42 CRISPRa kit - CRISPR gene activation of human DEAD-box helicase 42

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: DDX42
• Locus ID: 11325
• Components:

  GA107793G1, DDX42 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA107793G2, DDX42 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA107793G3, DDX42 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_007372, NM_203499
• UniProt ID: Q86XP3
• Synonyms: DDX42P; RHELP; RNAHP; SF3B8; SF3b125
• Summary: This gene encodes a member of the Asp-Glu-Ala-Asp (DEAD) box protein family. Members of this protein family are putative RNA helicases, and are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]