Human TDRKH activation kit by CRISPRa

SKU
GA107572
TDRKH CRISPRa kit - CRISPR gene activation of human tudor and KH domain containing
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol TDRKH
Locus ID 11022
Components

GA107572G1, TDRKH gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA107572G2, TDRKH gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA107572G3, TDRKH gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001083963, NM_001083964, NM_001083965, NM_006862
UniProt ID Q9Y2W6
Synonyms TDRD2
Summary Participates in the primary piRNA biogenesis pathway and is required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for the germline integrity. The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Required for the final steps of primary piRNA biogenesis by participating in the processing of 31-37 nt intermediates into mature piRNAs. May act in pi-bodies and piP-bodies by transferring piRNA precursors or intermediates to or between these granules.UniProtKB/Swiss-Prot Function
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Documents
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Other Versions
SKU Description Size Price
KN417780 TDRKH - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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