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Human IL24 activation kit by CRISPRa

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SKU
GA107559
IL24 CRISPRa kit - CRISPR gene activation of human interleukin 24
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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RC216502 IL24 (Myc-DDK-tagged)-Human interleukin 24 (IL24), transcript variant 1
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Other products for "IL24"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol IL24
Locus ID 11009
Components

GA107559G1, IL24 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA107559G2, IL24 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA107559G3, IL24 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001185156, NM_001185157, NM_001185158, NM_006850, NM_181339
UniProt ID Q13007
Synonyms C49A; FISP; IL10B; MDA7; MOB5; ST16
Summary This gene encodes a member of the IL10 family of cytokines. It was identified as a gene induced during terminal differentiation in melanoma cells. The protein encoded by this gene can induce apoptosis selectively in various cancer cells. Overexpression of this gene leads to elevated expression of several GADD family genes, which correlates with the induction of apoptosis. The phosphorylation of mitogen-activated protein kinase 14 (MAPK7/P38), and heat shock 27kDa protein 1 (HSPB2/HSP27) are found to be induced by this gene in melanoma cells, but not in normal immortal melanocytes. Alternatively spliced transcript variants encoding distinct isoforms have been reported. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN416502 IL24 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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