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Human SPINK5 activation kit by CRISPRa

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SKU
GA107556
SPINK5 CRISPRa kit - CRISPR gene activation of human serine peptidase inhibitor, Kazal type 5
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA315135 Rabbit polyclonal anti-SPINK5 antibody
100 ul
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RC226324 SPINK5 (Myc-DDK-tagged)-Human serine peptidase inhibitor, Kazal type 5 (SPINK5), transcript variant 1
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Other products for "SPINK5"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol SPINK5
Locus ID 11005
Components

GA107556G1, SPINK5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA107556G2, SPINK5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA107556G3, SPINK5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001127698, NM_001127699, NM_006846
UniProt ID Q9NQ38
Synonyms LEKTI; LETKI; NETS; NS; VAKTI
Summary This gene encodes a multidomain serine protease inhibitor that contains 15 potential inhibitory domains. The encoded preproprotein is proteolytically processed to generate multiple protein products, which may exhibit unique activities and specificities. These proteins may play a role in skin and hair morphogenesis, as well as anti-inflammatory and antimicrobial protection of mucous epithelia. Mutations in this gene may result in Netherton syndrome, a disorder characterized by ichthyosis, defective cornification, and atopy. This gene is present in a gene cluster on chromosome 5. Alternative splicing results in multiple transcript variants. provided by RefSeq, Oct 2015
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Documents
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Other Versions
SKU Description Size Price
KN423900 SPINK5 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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