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Human JAB1 (COPS5) activation kit by CRISPRa

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SKU
GA107543
COPS5 CRISPRa kit - CRISPR gene activation of human COP9 signalosome subunit 5
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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Other products for "COPS5"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol COPS5
Locus ID 10987
Components

GA107543G1, JAB1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA107543G2, JAB1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA107543G3, JAB1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_006837
UniProt ID Q92905
Synonyms CSN5; JAB1; MOV-34; SGN5
Summary The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN400979 COPS5 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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