Human SA2 (STAG2) activation kit by CRISPRa

SKU GA107355

STAG2 CRISPRa kit - CRISPR gene activation of human stromal antigen 2

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: STAG2
• Locus ID: 10735
• Components:

  GA107355G1, SA2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA107355G2, SA2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA107355G3, SA2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001042749, NM_001042750, NM_001042751, NM_001282418, NM_006603
• UniProt ID: Q8N3U4
• Synonyms: bA517O1.1; SA-2; SA2; SCC3B
• Summary: The protein encoded by this gene is a subunit of the cohesin complex, which regulates the separation of sister chromatids during cell division. Targeted inactivation of this gene results in chromatid cohesion defects and aneuploidy, suggesting that genetic disruption of cohesin is a cause of aneuploidy in human cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]