SA2 (STAG2) Rabbit Polyclonal Antibody

SKU TA350386

Rabbit Polyclonal Anti-STAG2 Antibody

Product Data

• Application: IHC, WB
• Recommended Dilution: WB: 200-1000; WB positive control: MCF7 cells; IHC: 25-100; Positive control: Human esophagus cancer; Predicted cell location: Nucleus
• Reactivity: Human, Mouse
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human STAG2
• Buffer: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 141 kDa
• Gene Name: stromal antigen 2
• Database Link:
  NP_006594
  Q8N3U4
• Background: The protein encoded by this gene is a subunit of the cohesin complex, which regulates the separation of sister chromatids during cell division. Targeted inactivation of this gene results in chromatid cohesion defects and aneuploidy, suggesting that genetic disruption of cohesin is a cause of aneuploidy in human cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Synonyms: bA517O1.1; SA-2; SA2; SCC3B

Reference Data

• Protein Pathways: Cell cycle