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Human PAK4 activation kit by CRISPRa

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SKU
GA107018
PAK4 CRISPRa kit - CRISPR gene activation of human p21 (RAC1) activated kinase 4
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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$447.00
RC217097 PAK4 (Myc-DDK-tagged)-Human p21 protein (Cdc42/Rac)-activated kinase 4 (PAK4), transcript variant 3
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Other products for "PAK4"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PAK4
Locus ID 10298
Components

GA107018G1, PAK4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA107018G2, PAK4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA107018G3, PAK4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001014831, NM_001014832, NM_001014833, NM_001014834, NM_001014835, NM_005884
UniProt ID O96013
Synonyms p21 protein (Cdc42/Rac)-activated kinase 4; p21(CDKN1A)-activated kinase 4; p21-activated kinase 4; protein kinase related to S. cerevisiae STE20, effector for Cdc42Hs
Summary PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. They serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases. PAK4 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN202302 PAK4 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN202302BN PAK4 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN202302LP PAK4 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN202302RB PAK4 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN402302 PAK4 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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