Human PREB activation kit by CRISPRa

SKU GA106861

PREB CRISPRa kit - CRISPR gene activation of human prolactin regulatory element binding

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: PREB
• Locus ID: 10113
• Components:

  GA106861G1, PREB gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA106861G2, PREB gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA106861G3, PREB gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001330484, NM_001330485, NM_001330486, NM_001330487, NM_013388, NR_138479
• UniProt ID: Q9HCU5
• Synonyms: SEC12
• Summary: This gene encodes a protein that specifically binds to a Pit1-binding element of the prolactin (PRL) promoter. This protein may act as a transcriptional regulator and is thought to be involved in some of the developmental abnormalities observed in patients with partial trisomy 2p. This gene overlaps the abhydrolase domain containing 1 (ABHD1) gene on the opposite strand. [provided by RefSeq, Jul 2008]