Human IL18BP activation kit by CRISPRa

SKU
GA106823
IL18BP CRISPRa kit - CRISPR gene activation of human interleukin 18 binding protein
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol IL18BP
Locus ID 10068
Components

GA106823G1, IL18BP gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA106823G2, IL18BP gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA106823G3, IL18BP gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001039659, NM_001039660, NM_001145055, NM_001145057, NM_005699, NM_173042, NM_173043, NM_173044
UniProt ID O95998
Synonyms IL18BPa
Summary The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. provided by RefSeq, Feb 2011
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Documents
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Other Versions
SKU Description Size Price
KN408111 IL18BP - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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