IL18BP Rabbit Polyclonal Antibody

SKU TA323375

Anti-IL18BP Rabbit Polyclonal Antibody

Product Data

• Application: IHC, WB
• Recommended Dilution: WB: 500-2000; WB positive control: MCF-7 cell lysate; IHC: 50-100; Positive control: Human prostate cancer; Predicted cell location: Cytoplasm
• Reactivity: Human
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to a region derived from 31-195 of Human Interleukin-18-binding protein
• Buffer: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Gene Name: interleukin 18 binding protein
• Database Link:
  NP_766631
  O95998
• Background: The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine; IL18. It binds IL18; prevents the binding of IL18 to its receptor; and thus inhibits IL18-induced IFN-gamma production; resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
• Synonyms: IL18BPa; interleukin 18 binding protein; MC51L-53L-54L homolog gene product; OTTHUMP00000179141; OTTHUMP00000179143; tadekinig-alfa

Reference Data

• Protein Families: Druggable Genome, Secreted Protein