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Human DMTF1 activation kit by CRISPRa

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SKU
GA106761
DMTF1 CRISPRa kit - CRISPR gene activation of human cyclin D binding myb like transcription factor 1
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA337244 Rabbit Polyclonal Anti-DMTF1 Antibody
100 ul
$585.00
RC209791 DMTF1 (Myc-DDK-tagged)-Human cyclin D binding myb-like transcription factor 1 (DMTF1), transcript variant 1
10 ug
$589.00 $696.00

Other products for "DMTF1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol DMTF1
Locus ID 9988
Components

GA106761G1, DMTF1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA106761G2, DMTF1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA106761G3, DMTF1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001142326, NM_001142327, NM_021145, NR_024549, NR_024550
UniProt ID Q9Y222
Synonyms DMP1; DMTF; hDMP1; MRUL
Summary This gene encodes a transcription factor that contains a cyclin D-binding domain, three central Myb-like repeats, and two flanking acidic transactivation domains at the N- and C-termini. The encoded protein is induced by the oncogenic Ras signaling pathway and functions as a tumor suppressor by activating the transcription of ARF and thus the ARF-p53 pathway to arrest cell growth or induce apoptosis. It also activates the transcription of aminopeptidase N and may play a role in hematopoietic cell differentiation. The transcriptional activity of this protein is regulated by binding of D-cyclins. This gene is hemizygously deleted in approximately 40% of human non-small-cell lung cancer and is a potential prognostic and gene-therapy target for non-small-cell lung cancer. Multiple transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Dec 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN409791 DMTF1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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