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Human HDAC4 activation kit by CRISPRa

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SKU
GA106565
HDAC4 CRISPRa kit - CRISPR gene activation of human histone deacetylase 4
  $1,657.00
4 Weeks*

Frequently Bought Together (1)

RC211495 HDAC4 (Myc-DDK-tagged)-Human histone deacetylase 4 (HDAC4)
10 ug
$1,415.00

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Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol HDAC4
Locus ID 9759
Components

GA106565G1, HDAC4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA106565G2, HDAC4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA106565G3, HDAC4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_006037
UniProt ID P56524
Synonyms AHO3; BDMR; HA6116; HD4; HDAC-4; HDAC-A; HDACA
Summary Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. provided by RefSeq, Jul 2008
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Documents
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Other Versions
SKU Description Size Price
KN411495 HDAC4 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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