Human MICAL2 activation kit by CRISPRa

SKU GA106462

MICAL2 CRISPRa kit - CRISPR gene activation of human microtubule associated monooxygenase, calponin and LIM domain containing 2

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: MICAL2
• Locus ID: 9645
• Components:

  GA106462G1, MICAL2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA106462G2, MICAL2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA106462G3, MICAL2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001282663, NM_001282664, NM_001282665, NM_001282666, NM_001282667, NM_001282668, NM_014632, NM_001346292, NM_001346293, NM_001346294, NM_001346295, NM_001346296, NM_001346297, NM_001346298, NM_001346299, NR_144415, NR_144416, NR_144417, NR_144418, NR_144419, NR_144420
• UniProt ID: O94851
• Synonyms: MICAL-2; MICAL2PV1; MICAL2PV2
• Summary: The protein encoded by this gene is a monooxygenase that enhances depolymerization of F-actin and is therefore involved in cytoskeletal dynamics. The encoded protein is a regulator of the SRF signaling pathway. Increased expression of this gene has been associated with cancer progression and metastasis. [provided by RefSeq, Oct 2016]