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Human PSMF1 activation kit by CRISPRa

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SKU
GA106343
PSMF1 CRISPRa kit - CRISPR gene activation of human proteasome inhibitor subunit 1
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA505275 PSMF1 mouse monoclonal antibody, clone OTI2D7 (formerly 2D7) 100 ul
$447.00
RC215482 PSMF1 (Myc-DDK-tagged)-Human proteasome (prosome, macropain) inhibitor subunit 1 (PI31) (PSMF1), transcript variant 2
10 ug
$300.00

Other products for "PSMF1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PSMF1
Locus ID 9491
Components

GA106343G1, PSMF1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA106343G2, PSMF1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA106343G3, PSMF1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001323407, NM_001323408, NM_001323409, NM_001323410, NM_006814, NM_178578, NM_178579
UniProt ID Q92530
Synonyms PI31
Summary The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a protein that inhibits the activation of the proteasome by the 11S and 19S regulators. Alternative transcript variants have been identified for this gene. provided by RefSeq, Jul 2008
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Other Versions
SKU Description Size Price
KN415482 PSMF1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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